Kaleido Scope

New model for replication of BKPyV virus, a major cause of kidney transplant failure

To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...

Precision work prior to cell division: How enzymes optimize DNA structure

Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists ...

Replicating bacterial DNA relies on accordion-like folds to separate, researchers discover

When bacteria cells replicate, they do so a little differently than human cells do. They don't undergo mitosis, a splitting ...
ucdavis.edu

Computational Model Uses Language Theory to Predict DNA Shapes That Underlie Gene Expression and Disease

R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...
Medical Xpress

Comparing DNA language models to guide optimal AI selection for genomics

Researchers at The University of Texas MD Anderson Cancer Center have performed a comprehensive evaluation of five artificial intelligence (AI) models trained on genomic sequences, known as DNA ...
Greek Reporter

Scientists Reveal Hidden Second Layer of Human DNA

Scientists reveal a hidden second layer of human DNA, showing how genome folding controls genes and influences disease development.
Science Daily

New model for replication of BKPyV virus, a major cause of kidney transplant failure

BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research reveals new aspects of BKPyV replication, offering possible drug targets ...