T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

There is a high unmet need for accessible, affordable, and high-quality fertility care, as approximately 1 in 6 people are affected by infertility worldwide. While meiotic failure is a major cause of ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages ...

The sugar glucose, which is the main source of energy in almost every living cell, has been revealed in a Stanford Medicine study to also be a master regulator of tissue differentiation - the process ...